Evaluation of sialometry and minor salivary gland biopsy in classification of Sjögren's Syndrome patients Summary
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[Evaluation of sialometry and minor salivary gland biopsy in classification of Sjögren's Syndrome patients].
UNLABELLED Sjögren's Syndrome is an autoimmune disease of the exocrine glands, mainly salivary and lachrymal glands. There is no gold standard test for diagnosis. AIM evaluation of the importance of minor salivary gland biopsy and sialometry, isolated or associated, as methods for classification of Sjögren's Syndrome. STUDY DESIGN Transversal cohort. PATIENTS AND METHOD Seventy-two patien...
متن کاملSialometry and sialochemistry: diagnostic tools for Sjögren's syndrome.
BACKGROUND The common occurrence of xerostomia in Sjögren's syndrome (SS) as well as the easy accessibility of saliva supports the use of sialometry and sialochemistry in the diagnosis of SS. Collection and analysis of whole saliva (oral fluid) is currently the routine technique for sialometry, despite the fact that it is rather inaccurate and impure. OBJECTIVE To assess the value of glandula...
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The recently observed low reproducibility of focus score (FS) assessment at different section depths in a series of single minor salivary gland biopsies highlighted the need for a standardized protocol of extensive histopathological examination of such biopsies in Sjogren's syndrome. For this purpose, a cumulative focus score (cFS) was evaluated on three slides cut at 200-mum intervals from eac...
متن کاملEvaluation of the concordance of sialometry and salivary glands scintigraphy in dry mouth patients.
INTRODUCTION Many diagnostic tests are used to evaluate dry mouth patients, especially the ones with Sjögren's Syndrome, to whom these tests are part of classification criteria for scientific studies. AIM Thus, the concordance between results of sialometry and salivary glands scintigraphy was evaluated; if positive, it would enable the choice of one or the other for diagnosis. PATIENTS AND ...
متن کاملThe minor salivary gland biopsy as a diagnostic tool for Sjogren syndrome.
OBJECTIVES/HYPOTHESIS In suspected cases of Sjogren syndrome (SS), patients are often referred for a labial minor salivary gland biopsy. However, studies have shown this test to be unreliable. Pathologic misinterpretation and immunosuppressive medications may affect the results of the biopsy. As a result, it is best to perform this procedure only when necessary. The purpose of the current study...
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